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The World's Longest-Running Refined Seed Oil Experiment

This table is from Dr Malcolm Kendrick's latest blog post, which is about the possibility of a retrospective "publication bias" deleting findings that don't support the lipid hypothesis on certain...

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Saturated Fat intake equivalent to 130g Butter a day is not significantly...

If you saw Professor Rod Jackson on NZ TV the other day, he was arguing, ably it has to be said, that the whole Big Fat Surprise / Time magazine cover, and by extension LCHF, risks reversing gains made...

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Where did the Butter go?

As I've said before in this blog, butter consumption in New Zealand was high in the 1940's, was halved by wartime rationing (1943-1948), rose again to its 1942/43 peak by the mid 60's, and is now a...

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Where did the butter go? Part 2

I had a look for an Edmonds Cookbook to prove my "peak butter = peak baking" thesis and came across something even more interesting; a League of Mothers Cook Book from what appears to be the 1970's...

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The Dietary habits of Otto von Bismarck

What Bismarck ate at the Siege of Paris (1870) :Bismarck's secretary, Dr Moritz Busch, who kept a detailed account of the great man's tabletalk, reveals that when he was not throwing out brutally...

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Dr Wilhelm Ebstein (1836-1912); the Father of LCHF, on Gout, 1884

"It is difficult to label Wilhelm Ebstein because he was a clinician, pathologist, chemist, basic scientist, teacher, and writer. It is a mystery that so few know him because he was extremely...

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The Time-Lag Diet-Heart Hypothesis - Last Ditch of Opposition to LCHF

In their “Against the Grain” Lancet letter, Jim Mann and co. cited a 2012 Swedish study[1] that correlated a rise in butter and fall in carbohydrate consumption with a later rise in serum cholesterol...

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Diabetes - an Evolutionary Hypothesis

        Hyperlipid wrote an interesting post a while back about the Inuit, and how a genetic mutation means that many of them are never in ketosis even eating a very low carb diet. Basically, the...

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Further Notes on Glucagon Dominant Hepatic Metabolism

The idea of the various forms of diabetes and pre-diabetes as a too ready susceptibility to glucagon dominance of hepatic metabolism, as described in the previous post, is not intended to diagnose or...

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The $64,000 Question

I've been obsessed with this question. It all started after reading the literature of pre-insulin treatment of diabetes and insulin-free animal models of the disease. Feeding fats and restricted...

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Some Answers to that Question

Let's back the truck right up to 1923. Insulin was introduced the year before and is now being mass produced by Eli Lilly & Co. Diet research into diabetes has crystallized into a proven diabetic...

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Testing the effect of a high fat diet in severe type 2 diabetes - Garg and...

It's all very well to test the metabolic effects of high-fat diets in RCTs. There are usually beneficial results in type 2 diabetes, but compliance is limited. The trial isn't showing what the diet...

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The Guinea Pig Model of Atherosclerosis

This is the kind of research that doesn't get as much attention as it used to.Animal models are vital ways of testing theories that it would be unethical to test on humans, and when theories or novel...

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Gluconeogenesis Drives Ketogenesis - role of the Nutritional Prometheus.

In trying to explain the findings of Newburgh and Marsh*, and of Karl Petren, from 1923 that switching to a high fat, restricted protein, and very low carbohydrate diet - a ketogenic diet - suppresses...

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Why the High-Fat Hep C Diet? Rationale and n=1 results.

I originally started this blog to publicise the hypothesis that a diet low in carbohydrate and linoleic acid, but high in saturated fat and long-chain PUFA, will inhibit HCV replication.The blog header...

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What, exactly, is the Dietary Guidelines for Americans Committee's case...

The 2015 DGA committee has released a 571 page document which is meant to inform the next dietary guidelines.[1] Changes are that % fat vs carbohydrate is no longer prescribed and cholesterol is no...

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TG/HDL ratio trumps LDL in untreated patients in the lipid lowering drug trials.

Ivor Cummins, bless him, found this treasure trove of data and broadcast it first on his Fat Emperor blog.I've decided to write about it here because Ivor, in his magpie style, has scooped it up and...

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How To Live Longer, by A. P. Herbert

This poem by A. P. Herbert was published in The Punch Guide to Good Living, under the initials A. P. H. The collection was edited by William Davis and published in 1973, and the selections appear to...

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The Acute Porphyrias, and other Contraindications for Very Low Carbohydrate...

From the Department of Due Diligence...Contraindications for Ketogenic and Very Low Carbohydrate DietsThis list of medical conditions which may cause adverse reactions to ketogenic diets or fasting may...

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Chemical Atherogenesis - the alternative hypothesis.

In 1977, when I was 19, and shortly before I cut my hair and joined a punk group, I worked as an apple picker in Upper Moutere, near Mapua, in the Tasman district of New Zealand.The orchard was an...

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