Fruit and Diabetes - some evidence
It's a commonly discussed paradox of sorts - how can fruit have a negative association with diabetes in epidemiology when it's full of sugar?Two recent papers from China go some way towards clearing...
View ArticleGilbert's Syndrome - a user's guide
Last week I received some liver test results from my last follow-up visit to Auckland Clinical Services after clearing HCV genotype 3 in the Phase 3 Epclusa trial mentioned here.ALT and AST were...
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Low fat dairy recommendations for children completely lack an evidence base,...
"There is no finer investment for any community than putting milk into babies."— Sir Winston Churchill (1874-1965) Radio broadcast (March 21, 1943)After reading about the Toddler Paradox on the Care...
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Fibre and the risk of Type 2 Diabetes - the InterAct meta-analysis
Recently the Australian government publicised claims generated by Nutrition Australia, in an opinion paper funded by Kellogg's, that Australians increasing their cereal fibre intake could reduce the...
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My first podcast interview, over at Break Nutrition
Raphi Sirt of Break Nutrition interviewed me last week for a podcast. This was a far-ranging interview that took me to some unexpected places - but was a chance to expand on the big-picture stuff and...
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Uncoupling - Saturated fatty acids and glucose are preferred muscle fuels,...
An intriguing new study looked at 2 different types of enteral feeding in 60 critically ill patients for 7 days. The fat-based formula was 37%E glucose, so this was not a test of a low carb diet, and...
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Never attribute to pathology what can be adequately explained by adaptive...
When this paper stumbled across my desk the other day my first thought was of course "Aha! Linoleic acid not so hot, this explains lack of benefit in RCTs as analysed by Steve Hamley".[1]Unsaturated...
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A Grand Unified Theory of Polyunsaturated Fatty Acid Misbehaviour in...
One of the great mysteries of nutrition is the behaviour of polyunsaturated fatty acids (PUFAs). They often look good in the kind of sloppy epidemiology used to drive or latterly protect dietary...
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Egregious - the Richard M. Fleming Story
An RCT paper claiming to show harmful effects of a low-carb diet passed briefly over the internet on the weekend before being shot down in flames. The title is:Long‐term health effects of the three...
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Don't Drink (oil) and Fry (in the sun) - the link between polyunsaturated...
It was good to see this well-researched burst of sunscreen scepticism doing the rounds this (southern) summer - Is Sunscreen the New Margarine? *I was particularly struck by the unintentionally ironic...
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Two important new papers on climate change.
Whad'ya mean, this has to last me a year?People in the LCHF community can be resistant to considering climate change and greenhouse gas levels because this argument can be used to shift the goalposts...
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Gene-diet interactions and the risk of colorectal cancer
There's nothing like a bit of cognitive dissonance to get the brain working if you steel yourself against the instinct to invoke protective stupidity. It's much like Marx's internal stresses of...
View ArticleThe Official COVID-19 protocol from Shanghai, China, in English
This detailed protocol, which appeared online last week on an official Chinese Govt website, includes high-dose Vitamin C within the SOC drug recommendations. So far, when this has been pointed out to...
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You can't Boost your Immunity? or, Debunking the COVID-19 Skeptics.
Kate's elderberry concoction, photograph by Hayley TheyersIs there anything as useless as the professional Skeptic community in a health crisis? Some people are paid to be roadblocks, others are...
View ArticleProbiotics for the prevention of Upper Respiratory Tract infections - a...
“With most people, disbelief in a thing is founded on a blind belief in something else" G. C. LichtenbergThe Cochrane Collaboration found low-quality evidence that probiotics prevent UTRIs, and...
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My Letter to Cochrane on the Hooper 2020 saturated fat meta
I submitted this on the Cochrane form athttps://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD011737.pub2/commentOthers will have points to add about study quality and other factors, I have stuck...
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A Reading List, and I Shill for a New Cookbook
It's been a time for reading lists; in lockdown I enjoyed discovering the books of T.H. White (The Goshawk and The Age of Scandal) and Evan S. Connell (Mrs Bridges) and reading Hillary Mantel's memoir...
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Selenium reduces COVID-19 risk - a back-of-the-envelope Bradford Hill analysis.
Bradford Hill introduced a checklist for assessing the strength of epidemiological evidence for causality, which is useful in the current pandemic when nutritional factors have been insufficiently...
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Mauritius - When the effects of saturated fat replacement failed to conform...
There may be no country in the world in which a suggested limit on saturated fat has not been followed by a relatively rapid increase in the incidence of diabetes and obesity.Of course this is a matter...
View ArticleLetter – Selenium supplementation may improve COVID-19 survival in sickle...
Further to Ulfberg and Stehlik’s letter of Sept 29th, further evidence supports the role of selenium in COVID-19 virulence.[1] In their pre-print analysis by machine learning of Medicare patients Dun...
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